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Microplasma-Enabled Surfaced-Functionalized Silicon Quantum Dots for Label-Free Detection of Dopamine.

ABSTRACT: Rapid and sensitive detection of dopamine (DA) is important for the diagnostics of neurological disorders and the development of new drugs. Here, we report microplasma synthesis of surfaced-functionalized silicon quantum dots (SiQDs) at ambient conditions. The synthesized SiQDs with useful properties including abundant surface functionalities, stable colloidal dispersion, and photoluminescence (PL) emission enable direct label-free detection of DA, providing a wide sensing range from 0.83 to 83.33 μM and a low detection limit of 0.32 μM. Our work provides a new direction for the synthesis of colloidal SiQDs and the understanding of SiQD-based PL probes for biomolecule sensing.

SUBMITTER: Chang GY

PROVIDER: S-EPMC8756587 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature

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Microplasma-Enabled Surfaced-Functionalized Silicon Quantum Dots for Label-Free Detection of Dopamine.

Chang Gui-Yi GY Kurniawan Darwin D Chang Yi-Ju YJ Chiang Wei-Hung WH

ACS omega 20211126 1

Rapid and sensitive detection of dopamine (DA) is important for the diagnostics of neurological disorders and the development of new drugs. Here, we report microplasma synthesis of surfaced-functionalized silicon quantum dots (SiQDs) at ambient conditions. The synthesized SiQDs with useful properties including abundant surface functionalities, stable colloidal dispersion, and photoluminescence (PL) emission enable direct label-free detection of DA, providing a wide sensing range from 0.83 to 83. ...[more]

PMID: 35036694

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