Comparison of oral metabolome profiles of stimulated saliva, unstimulated saliva, and mouth-rinsed water.

ABSTRACT: Saliva includes a substantial amount of biological information, which has enabled us to understand the relationship between oral metabolites and various oral and systemic disorders. However, collecting saliva using a controlled protocol is time-consuming, making saliva an unsuitable analyte in large cohort studies. Mouth-rinsed water (MW), the water used to rinse the mouth, can be collected easily in less time with less difference between subjects than saliva and could be used as an alternative in oral metabolome analyses. In this study, we investigated the potential of MW collection as an efficient alternative to saliva sample collection for oral metabolome profiling. MW, stimulated saliva, and unstimulated saliva were collected from 10 systemically healthy participants. The samples were

SUBMITTER: Maruyama Y 

PROVIDER: S-EPMC8758762 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature