Association between life-course cigarette smoking and metabolic syndrome: a discovery-replication strategy.

ABSTRACT:

Background

The relation between cigarette smoking and metabolic syndrome (MetS) remains unclear, and previous studies focusing on MetS are limited in sample size. We investigated the association between life-course smoking and MetS with independent discovery and replication samples.

Methods

Preliminary analysis utilized data from an annual cross-sectional survey of 15,222 participants aged ≥ 60 years in Tianjin, China. Suggestive associations were followed-up in 8565 adults from the China Health and Nutrition Survey. MetS was identified according to the criteria of the Chinese Diabetes Society in 2013. Life-course smoking was assessed by a comprehensive smoking index (CSI), based on information on smoking intensity, duration, and time since cessation across life-course, coll

SUBMITTER: Wang J 

PROVIDER: S-EPMC8761321 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature