AK098656: a new biomarker of coronary stenosis severity in hypertensive and coronary heart disease patients.

ABSTRACT:

Background

AK098656 may be an adverse factor for coronary heart disease (CHD), especially in patients with hypertension. This study aimed to analyze the effect of AK098656 on CHD and CHD with various complications.

Methods

A total of 117 CHD patients and 27 healthy control subjects were enrolled in the study. Plasma AK098656 expression was determined using the quantitative real-time polymerase chain reaction. Student's t-test was used to compare AK098656 expression levels in different groups. Receiver operating characteristic (ROC) curve and area under the curve (AUC) were used to quantify the discrimination ability between CHD patients and health controls and between CHD and CHD + complications patients. The relationship between AK098656 and coronary stenosis was analyzed u

SUBMITTER: Wang X 

PROVIDER: S-EPMC8761339 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature