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Guidelines on COVID-19 vaccination in patients with immune-mediated rheumatic diseases: a Brazilian Society of Rheumatology task force.


ABSTRACT:

Objective

To provide guidelines on the coronavirus disease 2019 (COVID-19) vaccination in patients with immune-mediated rheumatic diseases (IMRD) to rheumatologists considering specific scenarios of the daily practice based on the shared-making decision (SMD) process.

Methods

A task force was constituted by 24 rheumatologists (panel members), with clinical and research expertise in immunizations and infectious diseases in immunocompromised patients, endorsed by the Brazilian Society of Rheumatology (BSR), to develop guidelines for COVID-19 vaccination in patients with IMRD. A consensus was built through the Delphi method and involved four rounds of anonymous voting, where five options were used to determine the level of agreement (LOA), based on the Likert Scale: (1) strongly disagree; (2) disagree, (3) neither agree nor disagree (neutral); (4) agree; and (5) strongly agree. Nineteen questions were addressed and discussed via teleconference to formulate the answers. In order to identify the relevant data on COVID-19 vaccines, a search with standardized descriptors and synonyms was performed on September 10th, 2021, of the MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, and LILACS to identify studies of interest. We used the Newcastle-Ottawa Scale to assess the quality of nonrandomized studies.

Results

All the nineteen questions-answers (Q&A) were approved by the BSR Task Force with more than 80% of panelists voting options 4-agree-and 5-strongly agree-, and a consensus was reached. These Guidelines were focused in SMD on the most appropriate timing for IMRD patients to get vaccinated to reach the adequate covid-19 vaccination response.

Conclusion

These guidelines were developed by a BSR Task Force with a high LOA among panelists, based on the literature review of published studies and expert opinion for COVID-19 vaccination in IMRD patients. Noteworthy, in the pandemic period, up to the time of the review and the consensus process for this document, high-quality evidence was scarce. Thus, it is not a substitute for clinical judgment.

SUBMITTER: Tavares ACFMG 

PROVIDER: S-EPMC8762982 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature

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Guidelines on COVID-19 vaccination in patients with immune-mediated rheumatic diseases: a Brazilian Society of Rheumatology task force.

Tavares Anna Carolina Faria Moreira Gomes ACFMG   de Melo Ana Karla Guedes AKG   Cruz Vítor Alves VA   de Souza Viviane Angelina VA   de Carvalho Joana Starling JS   Machado Ketty Lysie Libardi Lira KLLL   de Azevedo Valadares Lilian David LD   Dos Reis Neto Edgard Torres ET   de Rezende Rodrigo Poubel Vieira RPV   de Resende Guimarães Maria Fernanda Brandão MFB   Ferreira Gilda Aparecida GA   de Sousa Braz Alessandra A   de Abreu Vieira Rejane Maria Rodrigues RMR   de Medeiros Pinheiro Marcelo M   Ribeiro Sandra Lúcia Euzébio SLE   Bica Blanca Elena Gomes Rios BEGR   Baptista Kátia Lino KL   da Costa Izaias Pereira IP   Marques Claudia Diniz Lopes CDL   Lopes Maria Lúcia Lemos MLL   Martinez José Eduardo JE   Giorgi Rina Dalva Neubarth RDN   da Mota Lícia Maria Henrique LMH   da Rocha Loures Marcos Antônio Araújo MAA   Dos Santos Paiva Eduardo E   Monticielo Odirlei André OA   Xavier Ricardo Machado RM   Kakehasi Adriana Maria AM   Pileggi Gecilmara Cristina Salviato GCS  

Advances in rheumatology (London, England) 20220117 1


<h4>Objective</h4>To provide guidelines on the coronavirus disease 2019 (COVID-19) vaccination in patients with immune-mediated rheumatic diseases (IMRD) to rheumatologists considering specific scenarios of the daily practice based on the shared-making decision (SMD) process.<h4>Methods</h4>A task force was constituted by 24 rheumatologists (panel members), with clinical and research expertise in immunizations and infectious diseases in immunocompromised patients, endorsed by the Brazilian Socie  ...[more]

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