Ontology highlight
ABSTRACT: Purpose
Medication nonadherence is prevalent in diabetic populations, with "forgetting" a commonly cited reason. This issue of forgetfulness is due, in part, to a failure of prospective memory (PM). Episodic future thinking (EFT) has been shown to improve PM but has not been used to improve medication adherence.Patients and methods
The current study used a multiple baseline design (N = 4) to test the effects of EFT on medication non-adherence for four patients with a diagnosis of type 2 diabetes or prediabetes, with comorbid high blood pressure or high cholesterol. Medication adherence was objectively measured over 15 weeks using medication event monitoring systems.Results
Results of visual analysis showed medication adherence was reliably improved, confirmed by mixed model analysis of variance (p < 0.001), with significant differences from baseline to treatment (Tau <0.05) for 3 of 4 participants. Improvements in two measures of PM (effect size (ES) = 0.73, 0.80) and delay discounting (ES = 1.20) were observed.Conclusion
This study provides a feasible way to improve medication adherence in patients with prediabetes or type 2 diabetes.
SUBMITTER: Epstein LH
PROVIDER: S-EPMC8763258 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Epstein Leonard H LH Jimenez-Knight Tatiana T Honan Anna M AM Paluch Rocco A RA Bickel Warren K WK
Patient preference and adherence 20220113
<h4>Purpose</h4>Medication nonadherence is prevalent in diabetic populations, with "forgetting" a commonly cited reason. This issue of forgetfulness is due, in part, to a failure of prospective memory (PM). Episodic future thinking (EFT) has been shown to improve PM but has not been used to improve medication adherence.<h4>Patients and methods</h4>The current study used a multiple baseline design (N = 4) to test the effects of EFT on medication non-adherence for four patients with a diagnosis of ...[more]