Ontology highlight
ABSTRACT:
SUBMITTER: Li X
PROVIDER: S-EPMC8771840 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Li Xiaoman X Wang Liang L Hao Jialin J Zhu Qingfeng Q Guo Min M Wu Changjing C Li Sihui S Guo Qiqiang Q Ren Qiuhong Q Bai Ning N Yi Fei F Jiang Bo B Zhang Wenyu W Feng Yanling Y Xu Hongde H Jiang Han H Zhai Xiaoyue X Zhang Guohua G Ji Hong-Long HL Yang Xuesong X Zhang Dan D Fu Jianhua J Chang Jianjun J Song Xiaoyu X Cao Liu L
International journal of biological sciences 20220101 3
The lamellar body (LB), a concentric structure loaded with surfactant proteins and phospholipids, is an organelle specific to type 2 alveolar epithelial cells (AT2). However, the origin of LBs has not been fully elucidated. We have previously reported that autophagy regulates Weibel-Palade bodies (WPBs) formation, and here we demonstrated that autophagy is involved in LB maturation, another lysosome-related organelle. We found that during development, LBs were transformed from autophagic vacuole ...[more]