Predicting Physical Appearance from DNA Data-Towards Genomic Solutions.

ABSTRACT: The idea of forensic DNA intelligence is to extract from genomic data any information that can help guide the investigation. The clues to the externally visible phenotype are of particular practical importance. The high heritability of the physical phenotype suggests that genetic data can be easily predicted, but this has only become possible with less polygenic traits. The forensic community has developed DNA-based predictive tools by employing a limited number of the most important markers analysed with targeted massive parallel sequencing. The complexity of the genetics of many other appearance phenotypes requires big data coupled with sophisticated machine learning methods to develop accurate genomic predictors. A significant challenge in developing universal genomic predictive methods

SUBMITTER: Pospiech E 

PROVIDER: S-EPMC8774670 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature