Browse
Submit Data
Databases
API
Help

Dataset Information

15 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Genes and Weightlifting Performance.

ABSTRACT: A recent case-control study identified 28 DNA polymorphisms associated with strength athlete status. However, studies of genotype-phenotype design are required to support those findings. The aim of the present study was to investigate both individually and in combination the association of 28 genetic markers with weightlifting performance in Russian athletes and to replicate the most significant findings in an independent cohort of Japanese athletes. Genomic DNA was collected from 53 elite Russian (31 men and 22 women, 23.3 ± 4.1 years) and 100 sub-elite Japanese (53 men and 47 women, 21.4 ± 4.2 years) weightlifters, and then genotyped using PCR or micro-array analysis. Out of 28 DNA polymorphisms, LRPPRC rs10186876 A, MMS22L rs9320823 T, MTHFR rs1801131 C, and PHACTR1 rs6905419 C alleles positively correlated (p < 0.05) with weightlifting performance (i.e., total lifts in snatch and clean and jerk in official competitions adjusted for sex and body mass) in Russian athletes. Next, using a polygenic approach, we found that carriers of a high (6-8) number of strength-related alleles had better competition results than carriers of a low (0-5) number of strength-related alleles (264.2 (14.7) vs. 239.1 (21.9) points; p = 0.009). These findings were replicated in the study of Japanese athletes. More specifically, Japanese carriers of a high number of strength-related alleles were stronger than carriers of a low number of strength-related alleles (212.9 (22.6) vs. 199.1 (17.2) points; p = 0.0016). In conclusion, we identified four common gene polymorphisms individually or in combination associated with weightlifting performance in athletes from East European and East Asian geographic ancestries.

SUBMITTER: Kikuchi N

PROVIDER: S-EPMC8775245 | biostudies-literature |

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Similar Datasets

Age-associated Performance Decline and Sex Differences in Olympic Weightlifting.

Project description:IntroductionThe rate of decline in physical performance for women is thought to be faster than that for men at any age in the Masters age classes in weightlifting and other sports. We quantified the age-associated decline in Olympic weightlifting separately for women and men and investigated possible impact of perimenopausal years on the performance decline.MethodsResults from Masters Weightlifting competitions from 1993 to 2018 were compiled from original score sheets and meet results made available by International Weightlifting Federation. Quantile curves were estimated for the age-related performance decline, and confidence intervals (CI) for the fractional performance with reference age 35 yr were calculated. Age-related decline curves were estimated for different periods to examine changes in performance levels.ResultsA total of 10,225 performance results for male and female weightlifters age 35 to 90 yr from 71 countries were included in the analysis. At age 40 yr compared with age 35 yr, the fractional performance is 0.947 (95% CI, 0.926-0.975), for men and 0.952 (95% CI. 0.898-0.986) for women while this is reduced to 0.723 (95% CI: 0.651-0.800) at age 60 yr for men and 0.604 (95% CI. 0.543-0.706) for women. Female performance levels before 2000 were worse; however, they have stabilized since 2013.ConclusionsThe performances of women weightlifters have improved over the last 25 yr. Thus, previous publications do not reflect current physical capabilities of women. The age-associated performance decline for female weightlifters mirrors the decline for men except for an accelerated decline during a 10-yr period across the age range from late 40s to late 50s thus coinciding with a transition into menopause.

| S-EPMC7028478 | biostudies-literature

Identifying a Test to Monitor Weightlifting Performance in Competitive Male and Female Weightlifters.

Project description:Monitoring tests are commonly used to assess weightlifter’s preparedness for competition. Although various monitoring tests have been used, it is not clear which test is the strongest indicator of weightlifting performance. Therefore, the purpose of this study was to (1) determine the relationships between vertical jump, isometric mid-thigh pull (IMTP) and weightlifting performance; and (2) compare vertical jumps to IMTP as monitoring tests of weightlifting performance in a large cohort of male and female weightlifters.Fifty-two competitive weightlifters (31 males, 21 females) participated in squat and countermovement jump testing (SJ, CMJ), and IMTP testing performed on force plates. All laboratory testing data was correlated to a recent competition where the athletes had attempted to peak.Squat jump height (SJH) was the strongest correlate for men and women with the Sinclair Total (r = 0.686, p ≤ 0.01; r = 0.487, p ≤ 0.05, respectively) compared to countermovement jump height (r = 0.642, p ≤ 0.01; r = 0.413, p = 0.063), IMTP peak force allometrically scaled to body mass (r = 0.542, p ≤ 0.01; r = −0.044, p = 0.851) and rate of force development at 200 ms (r = 0.066, p = 0.723; r = 0.086, p = 0.711), respectively. Further, SJH was a stronger correlate of relative weightlifting performance compared to IMTP peak force in females (p = 0.042), but not male weightlifters (p = 0.191).Although CMJ and IMTP are still considered strong indicators of weightlifting performance, SJH appears to be the most indicative measure of weightlifting performance across a wide-range of performance levels. Thus, SJH can be used as a reliable measure to monitor weightlifting performance in male and female weightlifters.

| S-EPMC6026842 | biostudies-literature

Effects of Dietary Nitrate Supplementation on Weightlifting Exercise Performance in Healthy Adults: A Systematic Review.

Project description:Dietary nitrate (NO3-) supplementation has been evidenced to induce an ergogenic effect in endurance and sprint-type exercise, which may be underpinned by enhanced muscle contractility and perfusion, particularly in type II muscle fibers. However, limited data are available to evaluate the ergogenic potential of NO3- supplementation during other exercise modalities that mandate type II fiber recruitment, such as weightlifting exercise (i.e., resistance exercise). In this systematic review, we examine the existing evidence basis for NO3- supplementation to improve muscular power, velocity of contraction, and muscular endurance during weightlifting exercise in healthy adults. We also discuss the potential mechanistic bases for any positive effects of NO3- supplementation on resistance exercise performance. Dialnet, Directory of Open Access Journals, Medline, Pubmed, Scielo, Scopus and SPORT Discus databases were searched for articles using the keywords: nitrate or beetroot and supplement or nut*r or diet and strength or "resistance exercise" or "resistance training" or "muscular power". Four articles fulfilling the inclusion criteria were identified. Two of the four studies indicated that NO3- supplementation could increase aspects of upper body weightlifting exercise (i.e., bench press) performance (increases in mean power/velocity of contraction/number of repetitions to failure), whereas another study observed an increase in the number of repetitions to failure during lower limb weightlifting exercise (i.e., back squat). Although these preliminary observations are encouraging, further research is required for the ergogenic potential of NO3- supplementation on weightlifting exercise performance to be determined.

| S-EPMC7469052 | biostudies-literature

Sex differences and impact of body mass on performance from childhood to senior athletes in Olympic weightlifting.

Project description:BACKGROUND:Olympic weightlifting requires technical skills, explosive power, strength, and coordination. Weightlifters can be competitive within a range of morphological characteristics due to competition body weight classes. To date no studies have examined when sex differences arise in weightlifting and the impact of body mass on performances at different ages. OBJECTIVES:To examine when sex-related differences emerge, to quantify the influence of body mass on performances at different ages, and to estimate the age at peak performance. METHODS:Competitions results from USA Weightlifting National Championships, Youth, Junior, and Senior from 2014 to 2019 were collected for weightlifters aged 6 to 30. RESULTS:At age 10 the median total weight lifted was 51kg and 54kg, respectively, for girls and boys. From age 10 to 12 a gender gap emerges with a sex difference of 11.7% at age 14 at 55kg body mass. At age 25 the sex-related performance difference is smaller for lighter athletes (23.6% at 69kg body mass) and larger for heavier athletes (29.9% at 81kg body mass). The median peak age for men is 26.5 years (95% CI: 25.7, 27.3) and for women 25.9 years (95% CI: 24.7, 27.3). CONCLUSION:We quantified the impact of body weight and age and sex differences for youth and young adults, ages 6 to 30 years old, participating in national level Olympic weightlifting competitions in the United States. Body weight at younger ages has less impact on performance compared to older ages, and boys and girls perform similarly. When reaching the ages typically associated with the onset of puberty, boys' performances rapidly increase and the gap between genders widens. Women achieve peak performance at a similar age than men. Such results may help to establish progression trajectories for talented athletes and inform coaches, athletes and national governing bodies.

| S-EPMC7470362 | biostudies-literature

Safety of weightlifting among women with or at risk for breast cancer-related lymphedema: musculoskeletal injuries and health care use in a weightlifting rehabilitation trial.

Project description:INTRODUCTION:It has been noted that only 14% of all clinical trials are translated into practice. The objective of this paper is to promote translation of an efficacious rehabilitative exercise program for breast cancer survivors by clarifying for clinicians the safety profile of participants (e.g., rates of musculoskeletal injury and referral to medical professionals), and to use this evidence to make recommendations on the appropriate training of health and fitness staff who would be capable of safely, effectively, and sustainably delivering the program. METHODS:Breast cancer survivors with and at risk for lymphedema were randomized to twice-weekly weightlifting or standard care for 1 year. An injury survey and health care evaluation were administered after 1 year and in 3-month intervals, respectively. RESULTS:The cumulative incidence and rate of injury were higher in the weightlifting than in the control group. The injury rates were 2.3 and 0.3 per 1,000 bouts of weightlifting among breast cancer survivors with and at risk for lymphedema, respectively. Among breast cancer survivors with or at risk for lymphedema, 20.9% in the weightlifting group had an encounter with a health care provider that required cessation or dose modification of weightlifting. CONCLUSION:Despite the demonstrated efficacy of weightlifting, musculoskeletal injuries and other health problems did occur. Therefore, for the successful translation of this rehabilitative intervention into clinical practice, health and fitness professionals working with breast cancer survivors need the knowledge, skills, and abilities that clarify their scope of practice to address these health care needs.

| S-EPMC3425531 | biostudies-literature

Validation of video analysis of marker-less barbell auto-tracking in weightlifting.

Project description:We determined the marker-less barbell auto-tracking accuracy using the Kanade-Lucas-Tomasi (KLT) algorithm in a digital video for two-dimensional analysis (2D-AT). The position coordinates of the barbell's right end during multiple loads (60%-90% of one-repetition maximum) of snatch motion in eight participants were recorded using a three-dimensional motion capture system. Simultaneously, the snatch motion was recorded by a digital camera from the right side. Based on the digital video, the center of the barbell's right end was auto-tracked using the KLT algorithm. Six barbell kinematic variables (forward, backward, and vertical displacement, peak forward, backward, and vertical velocity) were calculated. Intraclass correlation coefficient (ICC) analysis was performed to establish the agreement level between the methods. The Bland-Altman plots and regression were used to examine the agreement between the methods. ICCs of 0.999-0.971 revealed a strong agreement level between the methods. The Bland-Altman plot showed small bias (-0.001-0.001 m, -0.034 --0.005 m/s). We considered that 2D-AT could obtain barbell position coordinates with sufficient accuracy to discriminate the difference in the lifter's level and a successful or unsuccessful lift.

| S-EPMC8797250 | biostudies-literature

Effects of Pomegranate Juice Supplementation on Oxidative Stress Biomarkers Following Weightlifting Exercise.

Project description:The aim of this study was to test the hypothesis that pomegranate juice supplementation would blunt acute and delayed oxidative stress responses after a weightlifting training session. Nine elite weightlifters (21.0 ± 1 years) performed two Olympic-Weightlifting sessions after ingesting either the placebo or pomegranate juice supplements. Venous blood samples were collected at rest and 3 min and 48 h after each session. Compared to the placebo condition, pomegranate juice supplementation attenuated the increase in malondialdehyde (-12.5%; p < 0.01) and enhanced the enzymatic (+8.6% for catalase and +6.8% for glutathione peroxidase; p < 0.05) and non-enzymatic (+12.6% for uric acid and +5.7% for total bilirubin; p < 0.01) antioxidant responses shortly (3 min) after completion of the training session. Additionally, during the 48 h recovery period, pomegranate juice supplementation accelerated (p < 0.05) the recovery kinetics of the malondialdehyde (5.6%) and the enzymatic antioxidant defenses compared to the placebo condition (9 to 10%). In conclusion, supplementation with pomegranate juice has the potential to attenuate oxidative stress by enhancing antioxidant responses assessed acutely and up to 48 h following an intensive weightlifting training session. Therefore, elite weightlifters might benefit from blunted oxidative stress responses following intensive weightlifting sessions, which could have implications for recovery between training sessions.

| S-EPMC5579613 | biostudies-literature

The sonic instructor: A music-based biofeedback system for improving weightlifting technique.

Project description:In this study, we assumed that correct functional movements for weightlifting can be learned with the help of a music-based biofeedback system. We compared musical feedback with verbal feedback from experienced trainers using two independent groups. The focus was on one specific movement called deadlift. Physical parameters under considerations were the spine (i.e. loss of midline stability resulting in flexion) and the forward displacement of the barbell during the repetitions relative to the mid-foot. We recruited 31 recreational weight lifters (21-42 years of age). Results revealed that both feedback types are effective in improving the movements for deadlift. No significant differences were found across the two feedback types, neither in terms of movement, nor in terms of clarity and motivation. The results suggest that the proposed feedback system is a valid tool for technology-aided training and self-training practices.

| S-EPMC6713320 | biostudies-literature

The Masters athlete in Olympic weightlifting: Training, lifestyle, health challenges, and gender differences.

Project description:BackgroundOlympic weightlifting requires strength, speed, and explosive power. Vigorous physical activity such as Olympic weightlifting, for older adults has many benefits from improved strength, social interactions, and a healthy and independent lifestyle. Little is known about the training habits, health, and lifestyle of Masters weightlifters that includes top level athletes as well as beginners, and there is a dearth of data on women.ObjectivesThe primary aim was to describe demographics, training habits, and health including prevalence of injury and chronic disease in male and female Masters athletes in Olympic weightlifting. The secondary aim was to study gender differences and the age and impact of menopause on participation in the sport.ResultsThe 958 participants (46% men), ages 34 to 87, mostly train 3 to 4 days per week in 1 to 2 hour sessions. This is a highly educated and affluent group, 84% are white, 72% are married, 85% are post-secondary graduates. Exercise can also increase the risk of injury compared to less active older adults, but the rates of injury in weightlifting affecting training are lower than seen in other sports. The prevalence of depression and mental health is similar to a general population. Stress levels and sleep disturbances are more common among women than men. Women reach menopause at a similar age as women in industrialized countries, but menopausal symptoms constrained the training.ConclusionOlder athletes are capable of rigorous training programs and top performances while adjusting to changes due to biological aging. Weightlifting athletes, coaches, and health professionals must be aware of patterns of injuries and gender differences to incorporate successful prevention strategies. Knowledge of presentations of menopause and impact of menopausal symptoms on training allows women and health care providers to make informed treatment decisions.

| S-EPMC7717526 | biostudies-literature

Optimal strategies and cost-benefit analysis of the [Formula: see text]-player weightlifting game.

Project description:The study of cooperation has been extensively studied in game theory. Especially, two-player two-strategy games have been categorized according to their equilibrium strategies and fully analysed. Recently, a grand unified game covering all types of two-player two-strategy games, i.e., the weightlifting game, was proposed. In the present study, we extend this two-player weightlifting game into an [Formula: see text]-player game. We investigate the conditions for pure strategy Nash equilibria and for Pareto optimal strategies, expressed in terms of the success probability and benefit-to-cost ratio of the weightlifting game. We also present a general characterization of [Formula: see text]-player games in terms of the proposed game. In terms of a concrete example, we present diagrams showing how the game category varies depending on the benefit-to-cost ratio. As a general rule, cooperation becomes difficult to achieve as group size increases because the success probability of weightlifting saturates towards unity. The present study provides insights into achieving behavioural cooperation in a large group by means of a cost-benefit analysis.

| S-EPMC9120137 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data