Ontology highlight
ABSTRACT:
SUBMITTER: Li JQ
PROVIDER: S-EPMC8776480 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Li Jun-Qin JQ Jiang Hui-Jie HJ Su Xiu-Yun XY Feng Li L Zhan Na-Zhi NZ Li Shan-Shan SS Chen Zi-Jie ZJ Chang Bo-Han BH Cheng Peng-Zhen PZ Yang Liu L Pei Guo-Xian GX
Stem cells international 20220113
Schwann cells have been found to promote osteogenesis by an unclear molecular mechanism. To better understand how Schwann cells accelerate osteogenesis, RNA-Seq and LC-MS/MS were utilized to explore the transcriptomic and metabolic response of MC3T3-E1 to Schwann cells. Osteogenic differentiation was determined by ALP staining. Lentiviruses were constructed to alter the expression of Mif (macrophage migration inhibitory factor) in Schwann cells. Western blot (WB) analysis was employed to detect ...[more]