Ontology highlight
ABSTRACT:
SUBMITTER: Uellendahl-Werth F
PROVIDER: S-EPMC8776955 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Uellendahl-Werth Florian F Maj Carlo C Borisov Oleg O Juzenas Simonas S Wacker Eike Matthias EM Jørgensen Isabella Friis IF Steiert Tim Alexander TA Bej Saptarshi S Krawitz Peter P Hoffmann Per P Schramm Christoph C Wolkenhauer Olaf O Banasik Karina K Brunak Søren S Schreiber Stefan S Karlsen Tom Hemming TH Degenhardt Franziska F Nöthen Markus M Franke Andre A Folseraas Trine T Ellinghaus David D
Communications biology 20220120 1
Genetic correlations and an increased incidence of psychiatric disorders in inflammatory-bowel disease have been reported, but shared molecular mechanisms are unknown. We performed cross-tissue and multiple-gene conditioned transcriptome-wide association studies for 23 tissues of the gut-brain-axis using genome-wide association studies data sets (total 180,592 patients) for Crohn's disease, ulcerative colitis, primary sclerosing cholangitis, schizophrenia, bipolar disorder, major depressive diso ...[more]