A systematic review of the quality of reporting and risk of bias for randomized crossover trials in digestive disease journals.

ABSTRACT:

Background

The quality of randomized crossover studies on digestive diseases is unclear. We aimed to review crossover trials in digestive disease journals and evaluate their reporting quality and risk of bias.

Methods

We searched the PubMed, Web of Science, and Scopus databases for all crossover trials in 39 digestive journals between January 2011 and September 2021. Reporting adherence was based on the CONSORT 2010 statement: extension to randomized crossover trials published in July 2019. A newly released Cochrane risk of bias tool 2.0 extension for crossover trials was applied to assess the risk of bias.

Results

In total, 173 studies were included in the analysis, and 16.2% were published following the CONSORT statement extension. The crossover design was not only

SUBMITTER: Zhou Q 

PROVIDER: S-EPMC8777342 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature