Identification hub genes of consensus molecular subtype correlation with immune infiltration and predict prognosis in gastric cancer.
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ABSTRACT:
SUBMITTER: Yu X
PROVIDER: S-EPMC8777542 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
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Identification hub genes of consensus molecular subtype correlation with immune infiltration and predict prognosis in gastric cancer.
Yu Xin X Yu Bin B Fang Weidan W Xiong Jianping J Ma Mei M
Discover oncology 20211016 1
Gastric cancer (GC) has a great fatality rate, meanwhile, there is still a lack of available biomarkers for prognosis. The goal of the research was to discover key and novel potential biomarkers for GC. We screened for the expression of significantly altered genes based on survival rates from two consensus molecular subtypes (CMS) of GC. Subsequently, functional enrichment analysis showed these genes involved in many cancers. And we picked 6 hub genes that could both secreted in the tumor microe ...[more]
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