Ontology highlight
ABSTRACT:
SUBMITTER: Li S
PROVIDER: S-EPMC8779475 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Li Shuying S Wu Yanjuan Y Xue Xiukun X Liu Siyuan S
Polymers 20220111 2
The combination of chemotherapy, photothermal therapy (PTT) and photodynamic therapy (PDT) based on a single nanosystem is highly desirable for cancer treatment. In this study, we developed a versatile Pt(IV) prodrug-based nanodrug, PVPt@Cy NPs, to realize synchronous chemotherapy, PDT and PTT and integrate cancer treatment with bioimaging. To construct PVPt@Cy NPs, the amphiphilic Pt(IV)-based polymeric prodrug PVPt was synthesized by a facile one-pot coupling reaction, and then it was used to ...[more]