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ABSTRACT:
SUBMITTER: Lee SH
PROVIDER: S-EPMC8779965 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Lee Soo Hyun SH Kim Sunho S Yang Jun-Yeong JY Mun ChaeWon C Lee Seunghun S Kim Shin-Hyun SH Park Sung-Gyu SG
International journal of molecular sciences 20220117 2
Effective hotspot engineering with facile and cost-effective fabrication procedures is critical for the practical application of surface-enhanced Raman spectroscopy (SERS). We propose a SERS substrate composed of a metal film over polyimide nanopillars (MFPNs) with three-dimensional (3D) volumetric hotspots for this purpose. The 3D MFPNs were fabricated through a two-step process of maskless plasma etching and hydrogel encapsulation. The probe molecules dispersed in solution were highly concentr ...[more]