Ontology highlight
ABSTRACT:
SUBMITTER: Bayer P
PROVIDER: S-EPMC8782377 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Bayer Péter P Gatenby Robert A RA McDonald Patricia H PH Duckett Derek R DR Staňková Kateřina K Brown Joel S JS
PloS one 20220121 1
We propose a model of cancer initiation and progression where tumor growth is modulated by an evolutionary coordination game. Evolutionary games of cancer are widely used to model frequency-dependent cell interactions with the most studied games being the Prisoner's Dilemma and public goods games. Coordination games, by their more obscure and less evocative nature, are left understudied, despite the fact that, as we argue, they offer great potential in understanding and treating cancer. In this ...[more]