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The AlphaFold Database of Protein Structures: A Biologist's Guide.


ABSTRACT: AlphaFold, the deep learning algorithm developed by DeepMind, recently released the three-dimensional models of the whole human proteome to the scientific community. Here we discuss the advantages, limitations and the still unsolved challenges of the AlphaFold models from the perspective of a biologist, who may not be an expert in structural biology.

SUBMITTER: David A 

PROVIDER: S-EPMC8783046 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature

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The AlphaFold Database of Protein Structures: A Biologist's Guide.

David Alessia A   Islam Suhail S   Tankhilevich Evgeny E   Sternberg Michael J E MJE  

Journal of molecular biology 20211029 2


AlphaFold, the deep learning algorithm developed by DeepMind, recently released the three-dimensional models of the whole human proteome to the scientific community. Here we discuss the advantages, limitations and the still unsolved challenges of the AlphaFold models from the perspective of a biologist, who may not be an expert in structural biology. ...[more]

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