Identification of heart failure with preserved ejection fraction helps risk stratification for hypertrophic cardiomyopathy.

ABSTRACT:

Background

Heart failure with preserved ejection fraction (HFpEF) is the dominant form of heart failure (HF). We here aimed to investigate the characteristics and prognosis of HFpEF in patients with hypertrophic cardiomyopathy (HCM).

Methods

This was a prospective cohort study and patients with HCM with available NT-proBNP results were enrolled. Patients were categorized into HFpEF [defined as LVEF ≥50%, with symptoms or signs of HF, and N-terminal pro-brain natriuretic peptide ≥800 pg/mL according to American Heart Association (AHA) criteria] and without heart failure (non-HF). The outcomes of interest were all-cause death, cardiovascular death, and sudden cardiac death (SCD).

Results

Of 1178 included patients with HCM, 513 (43.5%) were identified as having HFpEF acc

SUBMITTER: Liu J 

PROVIDER: S-EPMC8790875 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature