Spontaneous quorum-sensing hierarchy reprogramming in Pseudomonas aeruginosa laboratory strain PAO1.
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ABSTRACT:
SUBMITTER: Cheng X
PROVIDER: S-EPMC8792115 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
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Spontaneous quorum-sensing hierarchy reprogramming in Pseudomonas aeruginosa laboratory strain PAO1.
Cheng Xiaoyan X Lu Mingqi M Qiu Huifang H Li Yuanhao Y Huang Linfeng L Dai Weijun W
AMB Express 20220126 1
Pseudomonas aeruginosa strain PAO1 has been commonly used in the laboratory, with frequent genome variations reported. Quorum sensing (QS), a cell-cell communication system, plays important role in controlling a variety of virulence factors. However, the evolution and adaptability of QS in those laboratory strains are still poorly understood. Here we used the QS reporter and whole-genome sequencing (WGS) to systematically investigate the QS phenotypes and corresponding genetic basis in collected ...[more]
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