Endoscopic Submucosal Dissection for Early Gastric Cancer in Elderly vs. Non-Elderly Patients: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objective

This study aimed to review the applicability and complications rate associated with endoscopic submucosal dissection (ESD) for early gastric cancer in elderly patients.

Methods

Databases of PubMed, Embase, CENTRAL, and ScienceDirect were searched till 15^th April 2021. All types of studies comparing ESD in the elderly vs non-elderly were included. Subgroup analysis was conducted for the following groups: ≥80 years vs <80 years, ≥75 years vs < 75 years, and ≥65 years vs <65 years.

Results

17 studies were included. Meta-analysis indicated no statistically significant difference in the en-bloc resection rates (OR: 0.92 95% CI: 0.68, 1.26 I² = 8% p=0.62) and histological complete resection rates (OR: 0.93 95% CI: 0.75, 1.15 I² = 2

SUBMITTER: Zhao J 

PROVIDER: S-EPMC8792970 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature