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Dataset Information

A comparative study of teriflunomide and dimethyl fumarate within the Swedish MS Registry.


ABSTRACT:

Background

Teriflunomide and dimethyl fumarate (DMF) are first-line disease-modifying treatments for multiple sclerosis with similar labels that are used in comparable populations.

Objectives

The objective of this study was to compare the effectiveness and persistence of teriflunomide and DMF in a Swedish real-world setting.

Methods

All relapsing-remitting multiple sclerosis (RRMS) patients in the Swedish MS registry initiating teriflunomide or DMF were included in the analysis. The primary endpoint was treatment persistence. Propensity score matching was used to adjust comparisons for baseline confounders.

Results

A total of 353 teriflunomide patients were successfully matched to 353 DMF. There was no difference in the rate of overall treatment discontinuation

SUBMITTER: Hillert J 

PROVIDER: S-EPMC8795225 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature

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