Dataset Information

Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Seroprevalence in Lebanon: A Population-Based Cross-Sectional Study

ABSTRACT:

Objectives

The World Health Organisation promoted the use of serological testing as a rapid and accurate technique for detection of the immunity against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In Lebanon, a better understanding of the immune response against SARS-CoV-2 is needed to develop effective measures for prevention and plan an appropriate national vaccination program. This study aims to measure the immunity status in Lebanon.

Methods

In this cross-sectional study, the population consisted of male and female Lebanese and non-Lebanese residents of Lebanon between the ages 15 and 75. Exclusion criteria included same household, symptomatic individuals, and extremes of age (<15 and >75). Representative testing for SARS-CoV-2 antibodies (Anti-SARS-CoV-2 electrochemiluminescence immunoassay/ECLIA) was used to assess the prevalence of SARS-CoV-2 infection in Lebanon.

Results

Over 6 months, a total of 13,755 participants were recruited, and 3,168 (23.03%) individuals tested positive for Anti-SARS-CoV-2, with levels of positivity varying among districts. A higher level of seropositivity was detected in the female participants.

Conclusion

The seroprevalence against SARS-CoV-2 varied within Lebanon and was compatible with the levels seen in the MENA region at the time of the study. The seroprevalence documented in this study reflected a level of immunity that is not protective at the national level.

Funding

This study was funded by the Lebanese American University School of Medicine.

SUBMITTER: Mahdi A

PROVIDER: S-EPMC8800496 | biostudies-literature |

REPOSITORIES: biostudies-literature

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