Ontology highlight
ABSTRACT:
SUBMITTER: Nowakowska MB
PROVIDER: S-EPMC8810926 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
Nowakowska Maria B MB Selby Katja K Przykopanski Adina A Krüger Maren M Krez Nadja N Dorner Brigitte G BG Dorner Martin B MB Jin Rongsheng R Minton Nigel P NP Rummel Andreas A Lindström Miia M
Scientific reports 20220202 1
Botulinum neurotoxins (BoNTs), produced by the spore-forming bacterium Clostridium botulinum, cause botulism, a rare but fatal illness affecting humans and animals. Despite causing a life-threatening disease, BoNT is a multipurpose therapeutic. Nevertheless, as the most potent natural toxin, BoNT is classified as a Select Agent in the US, placing C. botulinum research under stringent governmental regulations. The extreme toxicity of BoNT, its impact on public safety, and its diverse therapeutic ...[more]