Dataset Information

Adolescent valuation of CARIES-QC-U: a child-centred preference-based measure of dental caries.

ABSTRACT:

Objectives

This study develops an adolescent value set for a child-centred dental caries-specific measure of oral health-related quality of life (OHRQoL) based upon CARIES-QC (Caries Impacts and Experiences Questionnaire for Children). This study develops a new approach to valuing child health by eliciting adolescent preferences and anchoring these onto the 1-0 full health-dead QALY (quality adjusted life year) scale using ordinal adult preferences.

Methods

Two online surveys were created to elicit preferences for the CARIES-QC classification system. The first comprised best-worst scaling (BWS) tasks for completion by adolescents aged 11-16 years. The second comprised discrete choice experiment tasks with a duration attribute (DCE_TTO) for completion by adults aged over 18 years. Preferences were modelled using the conditional logit model. Mapping regressions anchored the adolescent BWS data onto the QALY scale using adult DCE_TTO values, since the BWS survey data alone cannot generate anchored values.

Results

723 adolescents completed the BWS survey and 626 adults completed the DCE_TTO survey. The samples were representative of UK adolescent and adult populations. Fully consistent and robust models were produced for both BWS and DCE_TTO data. BWS preferences were mapped onto DCE_TTO values, resulting utility estimates for each health state defined by the classification system.

Conclusion

This is the first measure with predetermined scoring based on preferences to be developed specifically for use in child oral health research, and uses a novel technique to generate a value set using adolescent preferences. The estimates can be used to generate QALYs in economic evaluations of interventions to improve children's oral health.

SUBMITTER: Rogers HJ

PROVIDER: S-EPMC8812216 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature

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Publications

Adolescent valuation of CARIES-QC-U: a child-centred preference-based measure of dental caries.

Rogers H J HJ Sagabiel J J Marshman Z Z Rodd H D HD Rowen D D

Health and quality of life outcomes 20220203 1

<h4>Objectives</h4>This study develops an adolescent value set for a child-centred dental caries-specific measure of oral health-related quality of life (OHRQoL) based upon CARIES-QC (Caries Impacts and Experiences Questionnaire for Children). This study develops a new approach to valuing child health by eliciting adolescent preferences and anchoring these onto the 1-0 full health-dead QALY (quality adjusted life year) scale using ordinal adult preferences.<h4>Methods</h4>Two online surveys were ...[more]

PMID: 35115013

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Project description:BackgroundCaries Impacts and Experiences Questionnaire for Children (CARIES-QC) is a child-centred caries-specific quality of life measure. This study aimed to select, and validate with children, a classification system for a paediatric condition-specific preference-based measure, based on CARIES-QC.MethodsFirst, a provisional classification system for a preference-based measure based on CARIES-QC was identified using Rasch analysis, psychometric testing, involvement of children and parents, and the developer of CARIES-QC. Second, qualitative, semi-structured 'think aloud' validation interviews were undertaken with a purposive sample of children with dental caries. The interviewer aimed to identify whether items were considered important and easily understood, whether any were overlapping and if any excluded items should be reintroduced. Interview recordings were transcribed verbatim and thematic analysis conducted.ResultsRasch analysis identified poor item spread for the items 'cross' and 'school'. Items relating to eating were correlated and the better performing items were considered for selection. Children expressed some confusion regarding the items 'school' and 'food stuck'. Parent representatives thought that impacts surrounding toothbrushing ('brushing') were encompassed by the item 'hurt'. Five items were selected from CARIES-QC for inclusion in the provisional classification system; 'hurt', 'annoy', 'carefully', 'kept awake' and 'cried'. Validation interviews were conducted with 20 children aged 5-16 years old. Participants thought the questionnaire was straightforward and covered a range of impacts. Children thought an item about certain foods being 'hard to eat' was more relevant than one about having to eat more carefully because of their teeth and so the 'carefully' item was replaced with 'hard to eat'.ConclusionFollowing child-centred modification, the preliminary five-item classification system is considered valid and suitable for use in a valuation survey. The innovative child-centred methods used to both identify and validate the classification system can be applied in the development of other preference-based measures.

Project description:BACKGROUND:Existing paediatric oral health-related quality of life (OHRQoL) measures are generic instruments designed to evaluate a range of oral conditions. It has been found that disease-specific measures may be more adept at detecting subtle changes which occur following treatment of the condition in question. Furthermore, existing self-report OHRQoL measures have not involved children at all stages of development of the measure. The aim of this study was to develop a caries-specific measure of quality of life for children. METHODS:The first stage of the study involved a qualitative enquiry with children, aged 5-16?years, to inform the development of the measure. Children generated the potential items, contributed to item reduction and questionnaire design and participated in the testing of face and content validity. The resulting measure was evaluated in a cross-sectional validation study. Ethical approval was granted for the study. RESULTS:The qualitative study found that children discussed a number of caries-related impacts which affected their daily lives. These were incorporated into a draft measure which was further refined following testing of face and content validity. This resulted in the production of the Caries Impacts and Experiences Questionnaire for Children (CARIES-QC), comprising 16 items and one global question. Two hundred participants with a mean (range) age of 8.1 (5-16) years took part in the further evaluation of CARIES-QC. Four items, which did not fit the Rasch model, were removed from further analysis. The remaining 12 items demonstrated good internal consistency (alpha?=?0.9) and the total score showed significant correlations with the number of decayed teeth, presence of pain, pulpal involvement, the Child Perceptions Questionnaire (16-item short form) and the global score (p?<?0.01, Spearman's rho). CONCLUSION:In conclusion, children's input allowed the development of a valid and reliable child-centred caries-specific quality of life measure. CARIES-QC can now be used to evaluate which interventions for dental caries are most effective in reducing impacts from the child's perspective.

Project description:Background:Forensic estimation of chronological age has played an increasingly important role as part of cadaver identification, and also in living individuals due to the phenomenon of immigration and sexual abuse of undocumented trafficked children. Objective:This research aimed to validate the already used dental mineralization and eruption atlas in normal children and adolescent population in estimating chronological age in a young population, particularly those with special needs, majority of them with systemic diseases. Participants and Setting:A sample of 163 orthopantomograms from two independent medical institutions was collected from 133 patients aged between 4 and 23 years. Method:The orthopantomograms were divided into two groups, 95 from patients with systemic pathologies that have repercussions on dental development and 68 with systemic pathologies without dental repercussions. Dental ages were estimated by the London Atlas using the left side and then independently the right side of the maxilla. The intraobserver and interobserver agreements were evaluated. The difference between dental age estimates and the chronological age and its absolute value were calculated and analyzed. Results:Statistically significant differences were found between estimates and chronological age, revealing a general prevalence for underestimation; except for those under the age of 12. Nevertheless, the underestimation in individuals under the age of 16 was not significant (with an average of less than one month), while the underestimation was significant for persons who were at least 16 years old (with an average over 26 months). Furthermore, for those persons with systemic diseases with dental repercussions a greater error in underestimation was obtained, which indicates that the midpoint values should be reassessed in persons with Down's syndrome, chromosomal alterations, syndromes and central nervous system disorders. Conclusions:This atlas can be potentially used as a tool for age estimation in a population with special needs and, also, in a population with systemic diseases, but we suggest further studies with larger international samples to create adequate atlases for all the required scenarios, mainly, diagrams for people with systemic diseases who are over the age of 16.

Dataset Information

Adolescent valuation of CARIES-QC-U: a child-centred preference-based measure of dental caries.

Objectives

Methods

Results

Conclusion

Publications

Adolescent valuation of CARIES-QC-U: a child-centred preference-based measure of dental caries.

Similar Datasets

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