Ontology highlight
ABSTRACT:
SUBMITTER: Falconieri A
PROVIDER: S-EPMC8822606 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
Falconieri Alessandro A Taparia Nikita N De Vincentiis Sara S Cappello Valentina V Sniadecki Nathan J NJ Raffa Vittoria V
Biophysical journal 20211231 3
New strategies to promote neuronal regeneration should aim to increase the speed of axonal elongation. Biochemical signaling is a key factor in axon growth, but recent discoveries have shown that mechanical force, through a process referred to as stretch growth, can significantly influence the elongation rate. Here, we develop a method to apply forces to primary hippocampal neurons from mice using magnetic microposts that actuate in response to an external magnetic field. Neurons are cultured on ...[more]