Ontology highlight
ABSTRACT:
SUBMITTER: Dagnew AF
PROVIDER: S-EPMC8827627 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Dagnew Alemnew F AF Vink Peter P Drame Mamadou M Willer David O DO Salaun Bruno B Schuind Anne E AE
Human vaccines & immunotherapeutics 20210630 11
Immunocompromised (IC) persons are at increased risk for herpes zoster (HZ) and its complications, mainly due to impairment of cell-mediated immunity (CMI). The adjuvanted recombinant zoster vaccine (RZV) demonstrated efficacy against HZ in autologous hematopoietic stem cell transplant (auto-HSCT) recipients and hematologic malignancy (HM) patients. We review immune responses to RZV in 5 adult IC populations, 4 of which were receiving multiple, concomitant immunosuppressive medications: auto-HSC ...[more]