Drug repurposing against SARS-CoV-2 using computational approaches.
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ABSTRACT:
SUBMITTER: Kumar S
PROVIDER: S-EPMC8830191 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Publications
Drug repurposing against SARS-CoV-2 using computational approaches.
Kumar Sumit S Kovalenko Svitlana S Bhardwaj Shakshi S Sethi Aaftaab A Gorobets Nikolay Yu NY Desenko Sergey M SM Poonam Rathi Brijesh B
Drug discovery today 20220210 7
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has generated a critical need for treatments to reduce morbidity and mortality associated with this disease. However, traditional drug development takes many years, which is not practical solution given the current pandemic. Therefore, a viable option is to repurpose existing drugs. The structural data of several proteins vital for the virus became available shortly after the start of the pandemic. In this review, we discu ...[more]
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