PD-L1 near Infrared Photoimmunotherapy of Ovarian Cancer Model.
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ABSTRACT:
SUBMITTER: Jin J
PROVIDER: S-EPMC8833482 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Publications
PD-L1 near Infrared Photoimmunotherapy of Ovarian Cancer Model.
Jin Jiefu J Sivakumar Ishwarya I Mironchik Yelena Y Krishnamachary Balaji B Wildes Flonné F Barnett James D JD Hung Chien-Fu CF Nimmagadda Sridhar S Kobayashi Hisataka H Bhujwalla Zaver M ZM Penet Marie-France MF
Cancers 20220126 3
(1) Background: Despite advances in surgical approaches and drug development, ovarian cancer is still a leading cause of death from gynecological malignancies. Patients diagnosed with late-stage disease are treated with aggressive surgical resection and chemotherapy, but recurrence with resistant disease is often observed following treatment. There is a critical need for effective therapy for late-stage ovarian cancer. Photoimmunotherapy (PIT), using an antibody conjugated to a near infrared (NI ...[more]
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