Ontology highlight
ABSTRACT:
SUBMITTER: Docherty KF
PROVIDER: S-EPMC8837825 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Docherty Kieran F KF Vaduganathan Muthiah M Solomon Scott D SD McMurray John J V JJV
JACC. Heart failure 20201001 10
Sacubitril/valsartan, an angiotensin receptor-neprilysin inhibitor (ARNI), has been shown to reduce the risk of cardiovascular death or heart failure hospitalization and improve symptoms among patients with chronic heart failure with reduced ejection fraction compared to enalapril, the gold standard angiotensin-converting enzyme inhibitor. In the 5 years since the publication of the results of PARADIGM-HF, further insight has been gained into integrating a neprilysin inhibitor into a comprehensi ...[more]