Ontology highlight
ABSTRACT:
SUBMITTER: Goyzueta-Mamani LD
PROVIDER: S-EPMC8838509 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Goyzueta-Mamani Luis Daniel LD Barazorda-Ccahuana Haruna Luz HL Chávez-Fumagalli Miguel Angel MA F Alvarez Karla Lucia KL Aguilar-Pineda Jorge Alberto JA Vera-Lopez Karin Jannet KJ Lino Cardenas Christian Lacks CL
Molecules (Basel, Switzerland) 20220128 3
<h4>Background</h4>Despite research on the molecular bases of Alzheimer's disease (AD), effective therapies against its progression are still needed. Recent studies have shown direct links between AD progression and neurovascular dysfunction, highlighting it as a potential target for new therapeutics development. In this work, we screened and evaluated the inhibitory effect of natural compounds from native Peruvian plants against tau protein, amyloid beta, and angiotensin II type 1 receptor (AT1 ...[more]