Ontology highlight
ABSTRACT:
SUBMITTER: Lin H
PROVIDER: S-EPMC8843937 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Lin Hui H Tian Shuo S Peng Yizhong Y Wu Ling L Xiao Yan Y Qing Xiangcheng X Shao Zengwu Z
Frontiers in cell and developmental biology 20220201
Low back pain (LBP) is a common musculoskeletal symptom, which brings a lot of pain and economic loss to patients. One of the most common causes of LBP is intervertebral disc degeneration (IVDD). However, pathogenesis is still debated, and therapeutic options are limited. Insulin-like growth factor (IGF) signaling pathways play an important role in regulating different cell processes, including proliferation, differentiation, migration, or cell death, which are critical to the homeostasis of tis ...[more]