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Experimental evidence for long-distance electrodynamic intermolecular forces.

ABSTRACT: Both classical and quantum electrodynamics predict the existence of dipole-dipole long-range electrodynamic intermolecular forces; however, these have never been hitherto experimentally observed. The discovery of completely new and unanticipated forces acting between biomolecules could have considerable impact on our understanding of the dynamics and functioning of the molecular machines at work in living organisms. Here, using two independent experiments, on the basis of different physical effects detected by fluorescence correlation spectroscopy and terahertz spectroscopy, respectively, we demonstrate experimentally the activation of resonant electrodynamic intermolecular forces. This is an unprecedented experimental proof of principle of a physical phenomenon that, having been observed for biomacromolecules and with long-range action (up to 1000 Å), could be of importance for biology. In addition to thermal fluctuations that drive molecular motion randomly, these resonant (and thus selective) electrodynamic forces may contribute to molecular encounters in the crowded cellular space.

SUBMITTER: Lechelon M

PROVIDER: S-EPMC8849397 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature

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Experimental evidence for long-distance electrodynamic intermolecular forces.

Lechelon Mathias M Meriguet Yoann Y Gori Matteo M Ruffenach Sandra S Nardecchia Ilaria I Floriani Elena E Coquillat Dominique D Teppe Frédéric F Mailfert Sébastien S Marguet Didier D Ferrier Pierre P Varani Luca L Sturgis James J Torres Jeremie J Pettini Marco M

Science advances 20220216 7

Both classical and quantum electrodynamics predict the existence of dipole-dipole long-range electrodynamic intermolecular forces; however, these have never been hitherto experimentally observed. The discovery of completely new and unanticipated forces acting between biomolecules could have considerable impact on our understanding of the dynamics and functioning of the molecular machines at work in living organisms. Here, using two independent experiments, on the basis of different physical effe ...[more]

PMID: 35171677

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Experimental evidence for long-distance electrodynamic intermolecular forces.

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Experimental evidence for long-distance electrodynamic intermolecular forces.

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