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Fatal myocarditis associated with acute parvovirus B19 and human herpesvirus 6 coinfection.


ABSTRACT: We report on the case of a healthy young boy who developed a fulminant myocarditis due to acute coinfection with erythrovirus (parvovirus B19) and human herpesvirus 6 (HHV-6) in the absence of an antiviral immune response. We suggest that the HHV-6-induced immunosuppression enhanced dissemination of parvovirus B19, which led to fatal myocarditis.

SUBMITTER: Rohayem J 

PROVIDER: S-EPMC88596 | biostudies-literature | 2001 Dec

REPOSITORIES: biostudies-literature

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Fatal myocarditis associated with acute parvovirus B19 and human herpesvirus 6 coinfection.

Rohayem J J   Dinger J J   Fischer R R   Klingel K K   Kandolf R R   Rethwilm A A  

Journal of clinical microbiology 20011201 12


We report on the case of a healthy young boy who developed a fulminant myocarditis due to acute coinfection with erythrovirus (parvovirus B19) and human herpesvirus 6 (HHV-6) in the absence of an antiviral immune response. We suggest that the HHV-6-induced immunosuppression enhanced dissemination of parvovirus B19, which led to fatal myocarditis. ...[more]

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