Ontology highlight
ABSTRACT:
SUBMITTER: Desai S
PROVIDER: S-EPMC8894079 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Desai Sanket S Dharavath Bhasker B Manavalan Sujith S Rane Aishwarya A Redhu Archana Kumari AK Sunder Roma R Butle Ashwin A Mishra Rohit R Joshi Asim A Togar Trupti T Apte Shruti S Bala Pratyusha P Chandrani Pratik P Chopra Supriya S Bashyam Murali Dharan MD Banerjee Anirban A Prabhash Kumar K Nair Sudhir S Dutt Amit A
NAR cancer 20220304 1
Persistent pathogen infection is a known cause of malignancy, although with sparse systematic evaluation across tumor types. We present a comprehensive landscape of 1060 infectious pathogens across 239 whole exomes and 1168 transcriptomes of breast, lung, gallbladder, cervical, colorectal, and head and neck tumors. We identify known cancer-associated pathogens consistent with the literature. In addition, we identify a significant prevalence of <i>Fusobacterium</i> in head and neck tumors, compar ...[more]