Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Semi-Crystalline Polyoxymethylene-co-Polyoxyalkylene Multi-Block Telechels as Building Blocks for Polyurethane Applications.

ABSTRACT: Hydroxy-terminated polyoxymethylene-co-polyoxyalkylene multi-block telechels were obtained by a new methodology that allows for the formal substituting of ether units in polyether polyols with oxymethylene moieties. An interesting feature is that, unlike carbonate groups in polycarbonate and polyethercarbonate polyols, homopolymer blocks of polyoxymethylene moieties can be formed. The regular nature of polyoxymethylene blocks imparts a certain crystallinity to the polymer that can give rise to new properties of polyurethanes derived from such telechels. The synthesis, reaction sequence and kinetics of the formation of oligomeric hydroxy-terminated multi-block telechel polyoxymethylene moieties are discussed in this paper and the preparation of a polyurethane material is demonstrated.

SUBMITTER: Hoffmann M

PROVIDER: S-EPMC8912848 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Publications

Semi-Crystalline Polyoxymethylene-<i>co</i>-Polyoxyalkylene Multi-Block Telechels as Building Blocks for Polyurethane Applications.

Hoffmann Matthias M Hermesmann Matthias M Leven Matthias M Leitner Walter W Müller Thomas Ernst TE

Polymers 20220223 5

Hydroxy-terminated polyoxymethylene-<i>co</i>-polyoxyalkylene multi-block telechels were obtained by a new methodology that allows for the formal substituting of ether units in polyether polyols with oxymethylene moieties. An interesting feature is that, unlike carbonate groups in polycarbonate and polyethercarbonate polyols, homopolymer blocks of polyoxymethylene moieties can be formed. The regular nature of polyoxymethylene blocks imparts a certain crystallinity to the polymer that can give ri ...[more]

PMID: 35267705

Similar Datasets

Heterogenous electromediated depolymerization of highly crystalline polyoxymethylene.

Project description:Post-consumer plastic waste in the environment has driven the scientific community to develop deconstruction methods that yield valued substances from these synthetic macromolecules. Electrocatalysis is a well-established method for achieving challenging transformations in small molecule synthesis. Here we present the first electro-chemical depolymerization of polyoxymethylene-a highly crystalline engineering thermoplastic (Delrin®)-into its repolymerizable monomer, formaldehyde/1,3,5-trioxane, under ambient conditions. We investigate this electrochemical deconstruction by employing solvent screening, cyclic voltammetry, divided cell studies, electrolysis with redox mediators, small molecule model studies, and control experiments. Our findings determine that the reaction proceeds via a heterogeneous electro-mediated acid depolymerization mechanism. The bifunctional role of the co-solvent 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) is also revealed. This study demonstrates the potential of electromediated depolymerization serving as an important role in sustainable chemistry by merging the concepts of renewable energy and circular plastic economy.

| S-EPMC10415396 | biostudies-literature

Surface chiroselective assembly of enantiopure crystalline porous films containing bichiral building blocks.

Project description:The development of chiral crystalline porous materials (CPMs) containing multiple chiral building blocks plays an important role in chiral chemistry and applications but is a challenging task. Herein, we report the first example of bichiral building block based enantiopure CPM films containing metal-organic cages (MOCs) and metal complexes. The functionalized substrate was immersed subsequently into homochiral metal complex (R)- or (S)-Mn(DCH)3 (DCH = 1,2-diaminocyclohexane) and racemic Ti4L6 cage (L = embonate) solutions by a layer-by-layer growth method. During the assembly process, the substrate surface coordinated with (R)- or (S)-Mn(DCH)3 can, respectively, layer-by-layer chiroselectively connect Δ- or Λ-Ti4L6 cages to form homochiral (R, Δ)- or (S, Λ)-CPM films with a preferred [111] growth orientation, tunable thickness and homogeneous surface. The resulting enantiopure CPM films show strong chirality, photoluminescence, and circularly polarized luminescence (CPL) properties as well as good enantioselective adsorption toward enantiomers of 2-butanol and methyl-lactate. The present in situ surface chiroselective strategy opens a new route to assemble homochiral CPM films containing multiple chiral building blocks for chiral applications.

| S-EPMC8480342 | biostudies-literature

Biomaterials from the sea: Future building blocks for biomedical applications.

Project description:Marine resources have tremendous potential for developing high-value biomaterials. The last decade has seen an increasing number of biomaterials that originate from marine organisms. This field is rapidly evolving. Marine biomaterials experience several periods of discovery and development ranging from coralline bone graft to polysaccharide-based biomaterials. The latter are represented by chitin and chitosan, marine-derived collagen, and composites of different organisms of marine origin. The diversity of marine natural products, their properties and applications are discussed thoroughly in the present review. These materials are easily available and possess excellent biocompatibility, biodegradability and potent bioactive characteristics. Important applications of marine biomaterials include medical applications, antimicrobial agents, drug delivery agents, anticoagulants, rehabilitation of diseases such as cardiovascular diseases, bone diseases and diabetes, as well as comestible, cosmetic and industrial applications.

| S-EPMC8102716 | biostudies-literature

Sequence-Defined Oligomers from Hydroxyproline Building Blocks for Parallel Synthesis Applications.

Project description:The functionality of natural biopolymers has inspired significant effort to develop sequence-defined synthetic polymers for applications including molecular recognition, self-assembly, and catalysis. Conjugation of synthetic materials to biomacromolecules has played an increasingly important role in drug delivery and biomaterials. We developed a controlled synthesis of novel oligomers from hydroxyproline-based building blocks and conjugated these materials to siRNA. Hydroxyproline-based monomers enable the incorporation of broad structural diversity into defined polymer chains. Using a perfluorocarbon purification handle, we were able to purify diverse oligomers through a single solid-phase extraction method. The efficiency of synthesis was demonstrated by building 14 unique trimers and 4 hexamers from 6 diverse building blocks. We then adapted this method to the parallel synthesis of hundreds of materials in 96-well plates. This strategy provides a platform for the screening of libraries of modified biomolecules.

| S-EPMC5245870 | biostudies-literature

Toward Upscaled Biocatalytic Preparation of Lactone Building Blocks for Polymer Applications.

Project description:Although Baeyer-Villiger monooxygenases (BVMOs) have gained attention in recent years, there are few cases of their upscaled application for lactone synthesis. A thermostable cyclohexanone monooxygenase from Thermocrispum municipale (TmCHMO) was applied to the oxidation of 3,3,5-trimethylcyclohexanone using a glucose dehydrogenase (GDH) for cofactor regeneration. The reaction progress was improved by optimizing the biocatalyst loading, with investigation into oxygen limitations. The product concentration and productivity were increased by keeping the substrate concentration below the inhibitory level via continuous substrate feeding (CSF). This substrate feeding strategy was evaluated against two biphasic reactions using either toluene or n-butyl acetate as immiscible organic solvents. A product concentration of 38 g L-1 and a space-time yield of 1.35 g L-1 h-1 were achieved during the gram-scale synthesis of the two regioisomeric lactones by applying the CSF strategy. These improvements contribute to the large-scale application of BVMOs in the synthesis of branched building blocks for polymer applications.

| S-EPMC6156103 | biostudies-literature

Benzenedisulfonic Acid as an ALD/MLD Building Block for Crystalline Metal-Organic Thin Films*.

Project description:Two new atomic/molecular layer deposition processes for depositing crystalline metal-organic thin films, built from 1,4-benzenedisulfonate (BDS) as the organic linker and Cu or Li as the metal node, are reported. The processes yield in-situ crystalline but hydrated Cu-BDS and Li-BDS films; in the former case, the crystal structure is of a previously known metal-organic-framework-like structure, while in the latter case not known from previous studies. Both hydrated materials can be readily dried to obtain the crystalline unhydrated phases. The stability and the ionic conductivity of the unhydrated Li-BDS films were characterized to assess their applicability as a thin film solid polymer Li-ion conductor.

| S-EPMC8251735 | biostudies-literature

New building blocks in the 2/1 crystalline approximant of a Bergman-type icosahedral quasicrystal.

Project description:The refined x-ray crystal structure of the phase Mg(27)Al(10.7(2))Zn(47.3(2)) (Pa3) establishes it as the new 2/1 Bergman-type approximant of the icosahedral quasicrystal. The primitive cubic lattice consists of condensed triacontahedral and novel prolate rhombohedral (PR) clusters. Each triacontahedron encapsulates the traditional, multiply endohedral Bergman-type clusters, and each PR encapsulates an Al(2) dimer. This phase exhibits the same long-range order as recently established for the Tsai-type Sc-Mg-Zn 2/1 approximant crystal, with substantial geometric and atomic distribution differences between the two only in the short range orders. This common feature suggests that Bergman- and Tsai-type quasicrystals may be more similar than earlier conceived. Factors germane to the formation of, and the differences between, Bergman- vs. Tsai-type 1/1 and 2/1 approximate structures are considered, including notably different distributions of the more electropositive elements.

| S-EPMC1564238 | biostudies-literature

Morphology and Degradation of Multicompartment Microparticles Based on Semi-Crystalline Polystyrene-block-Polybutadiene-block-Poly(L-lactide) Triblock Terpolymers.

Project description:The confinement assembly of block copolymers shows great potential regarding the formation of functional microparticles with compartmentalized structure. Although a large variety of block chemistries have already been used, less is known about microdomain degradation, which could lead to mesoporous microparticles with particularly complex morphologies for ABC triblock terpolymers. Here, we report on the formation of triblock terpolymer-based, multicompartment microparticles (MMs) and the selective degradation of domains into mesoporous microparticles. A series of polystyrene-block-polybutadiene-block-poly(L-lactide) (PS-b-PB-b-PLLA, SBL) triblock terpolymers was synthesized by a combination of anionic vinyl and ring-opening polymerization, which were transformed into microparticles through evaporation-induced confinement assembly. Despite different block compositions and the presence of a crystallizable PLLA block, we mainly identified hexagonally packed cylinders with a PLLA core and PB shell embedded in a PS matrix. Emulsions were prepared with Shirasu Porous Glass (SPG) membranes leading to a narrow size distribution of the microparticles and control of the average particle diameter, d ≈ 0.4 µm-1.8 µm. The core-shell cylinders lie parallel to the surface for particle diameters d < 0.5 µm and progressively more perpendicular for larger particles d > 0.8 µm as verified with scanning and transmission electron microscopy and particle cross-sections. Finally, the selective degradation of the PLLA cylinders under basic conditions resulted in mesoporous microparticles with a pronounced surface roughness.

| S-EPMC8706259 | biostudies-literature

Peri-Alkylated Terrylenes and Ternaphthalenes Building-Blocks Towards Multi-Edge Nanographenes.

Project description:Since its first synthesis by Clar in 1948, terrylene - a fully connected ternaphthalene oligomer via naphthalene's peri-positions - has gained special focus within the rylene family, drawing interest for its unique chemical, structural, optoelectronic and single photon emission properties. In this study, we introduce a novel synthetic pathway that enhances the solubility of terrylene derivatives through complete peri-alkylation, while also facilitating extensions at the bay-positions. This approach not only broadens the scope of terrylene's chemical versatility but also opens new avenues for developing solution processable novel multi-edge nanographenes and tailoring electronic energy levels through topological edge structures. Our findings include a comprehensive structural and spectroscopic characterization along with transient absorption spectroscopy and photophysics of both the synthesized peri-alkylated terrylene and its phenylene-fused derivative.

| S-EPMC11497246 | biostudies-literature

Non-Canonical Amino Acids as Building Blocks for Peptidomimetics: Structure, Function, and Applications.

Project description:This review provides a fresh overview of non-canonical amino acids and their applications in the design of peptidomimetics. Non-canonical amino acids appear widely distributed in nature and are known to enhance the stability of specific secondary structures and/or biological function. Contrary to the ubiquitous DNA-encoded amino acids, the structure and function of these residues are not fully understood. Here, results from experimental and molecular modelling approaches are gathered to classify several classes of non-canonical amino acids according to their ability to induce specific secondary structures yielding different biological functions and improved stability. Regarding side-chain modifications, symmetrical and asymmetrical α,α-dialkyl glycines, Cα to Cα cyclized amino acids, proline analogues, β-substituted amino acids, and α,β-dehydro amino acids are some of the non-canonical representatives addressed. Backbone modifications were also examined, especially those that result in retro-inverso peptidomimetics and depsipeptides. All this knowledge has an important application in the field of peptidomimetics, which is in continuous progress and promises to deliver new biologically active molecules and new materials in the near future.

| S-EPMC10296201 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data