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Adjuvant Treatment of Elderly Breast Cancer Patients: Offer the Best Chances of Cure.


ABSTRACT:

Background

Breast cancer remains the most common cancer in women and a leading cause of death. Elderly people have a higher incidence of breast cancer since it increases with age. Furthermore, the extended life expectancy and advances in imaging techniques have led to an increased number of cases. Guidelines concerning the management of this specific age group are rare, mainly due to underrepresentation of seniors in clinical trials. Moreover, increased frailty, comorbidities, and a poor performance status make it complex to determine the best therapeutic approach.

Summary

In this review, we attempt to summarize the current literature and aim to provide specific approaches and recommendations for prompt diagnosis, treatment, and management of breast cancer in the elderly.

Key messages

The establishment of applicable protocols is imperative and efforts are being made in this direction. A careful geriatric assessment and adequate consultation should be the standard of care and patient's preferences should always be considered.

SUBMITTER: Marinopoulos S 

PROVIDER: S-EPMC8914240 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature

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Adjuvant Treatment of Elderly Breast Cancer Patients: Offer the Best Chances of Cure.

Marinopoulos Spyridon S   Dimitrakakis Constantine C   Kalampalikis Andreas A   Zagouri Flora F   Andrikopoulou Angeliki A   Rodolakis Alexandros A  

Breast care (Basel, Switzerland) 20210304 1


<h4>Background</h4>Breast cancer remains the most common cancer in women and a leading cause of death. Elderly people have a higher incidence of breast cancer since it increases with age. Furthermore, the extended life expectancy and advances in imaging techniques have led to an increased number of cases. Guidelines concerning the management of this specific age group are rare, mainly due to underrepresentation of seniors in clinical trials. Moreover, increased frailty, comorbidities, and a poor  ...[more]

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