The P132H mutation in the main protease of Omicron SARS-CoV-2 decreases thermal stability without compromising catalysis or small-molecule drug inhibition.
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ABSTRACT:
SUBMITTER: Sacco MD
PROVIDER: S-EPMC8923085 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
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The P132H mutation in the main protease of Omicron SARS-CoV-2 decreases thermal stability without compromising catalysis or small-molecule drug inhibition.
Sacco Michael Dominic MD Hu Yanmei Y Gongora Maura Verenice MV Meilleur Flora F Kemp Michael Trent MT Zhang Xiujun X Wang Jun J Chen Yu Y
Cell research 20220315 5
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