Ontology highlight
ABSTRACT:
SUBMITTER: Dalimot JJ
PROVIDER: S-EPMC8949899 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Dalimot Jill Jasmine JJ Smith Ilka Mc Cormick IMC Gerkrath Jasmin J Hartmann Sylvia S Cornely Oliver A OA Lee Soo Chan SC Heitman Joseph J Rickerts Volker V
Journal of fungi (Basel, Switzerland) 20220311 3
Mucormycosis is an invasive fungal infection associated with high mortality, partly due to delayed diagnosis and inadequate empiric therapy. As fungal cultures often fail to grow Mucorales, identification of respective hyphae in tissue is frequently needed for diagnosis but may be challenging. We studied fluorescence in situ hybridization (FISH) targeting specific regions of the fungal ribosomal RNA (rRNA) of Mucorales to improve diagnosis of mucormycosis from tissue samples. We generated a prob ...[more]