Effects of F171 mutations in the 6'-N-acetyltransferase type Ib [AAC(6')-Ib] enzyme on susceptibility to aminoglycosides.
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ABSTRACT:
SUBMITTER: Chavideh R
PROVIDER: S-EPMC89568 | biostudies-literature | 1999 Nov
REPOSITORIES: biostudies-literature
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Effects of F171 mutations in the 6'-N-acetyltransferase type Ib [AAC(6')-Ib] enzyme on susceptibility to aminoglycosides.
Chavideh R R Sholly S S Panaite D D Tolmasky M E ME
Antimicrobial agents and chemotherapy 19991101 11
Substitutions at position F171 of 6'-N-acetyltransferase type Ib cause variable loss of aminoglycoside resistance, indicating that this residue plays an important role in the structure and/or function of the enzyme. ...[more]
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