Ontology highlight
ABSTRACT:
SUBMITTER: Shanti A
PROVIDER: S-EPMC8964734 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Shanti Aya A Al Adem Kenana K Stefanini Cesare C Lee Sungmun S
Scientific reports 20220329 1
Phosphate ions are the most abundant anions inside the cells, and they are increasingly gaining attention as key modulators of cellular function and gene expression. However, little is known about the effect of inorganic phosphate ions on cancer cells, particularly breast cancer cells. Here, we investigated the toxicity of different phosphate compounds to triple-negative human breast cancer cells, particularly, MDA-MB-231, and compared it to that of human monocytes, THP-1. We found that, unlike ...[more]