Efficacy of different anticoagulant doses for patients with COVID-19: a systematic review and network meta-analysis.

ABSTRACT:

Purpose

As no reported randomized control trials (RCTs) directly compare the three administration doses of anticoagulants (prophylactic dose, treatment dose, and no treatment), the most recommended dose to be administered to patients with coronavirus disease 2019 (COVID-19) remains unclear. The purpose of this study was to examine the effects of anticoagulant doses administered to patients with COVID-19, using a network meta-analysis (NMA) including high-quality studies.

Methods

All eligible trials from the Cochrane Central Register of Controlled Trials, MEDLINE, and Clinicaltrials.gov were included. We included RCTs and observational studies adjusted for covariates for patients aged ≥ 18 years and hospitalized due to objectively confirmed COVID-19. The main study outcome wa

SUBMITTER: Yasuda H 

PROVIDER: S-EPMC8966866 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature