The role of age in treatment decisions for oral cavity squamous cell carcinoma: Analysis of the National Cancer Database.

ABSTRACT:

Background

The number of elderly patients with oral squamous cell carcinoma (OCSCC) is increasing as the elderly population increases. Unfortunately, evidence to guide the management of these patients is lacking.

Methods

Patients with OCSCC identified from the National Cancer Database (NCDB) were stratified into age-based cohorts. Demographics, comorbidities, and treatment patterns were analyzed. Patients were stratified into early stage (Stage I/II) and advanced stage (Stage III/IV) disease. The likelihood of receiving multimodality therapy by age was calculated using multinomial logistic regression for each stratum while controlling for potential confounders. Cox proportional hazard regression was used to calculate 5-year mortality risk while controlling for potential conf

SUBMITTER: Barrett TF 

PROVIDER: S-EPMC8984992 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature