Geographic distribution of a large mobile element that transfers ampicillin and vancomycin resistance between Enterococcus faecium strains.
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ABSTRACT:
SUBMITTER: Hanrahan J
PROVIDER: S-EPMC89868 | biostudies-literature | 2000 May
REPOSITORIES: biostudies-literature
Publications
Geographic distribution of a large mobile element that transfers ampicillin and vancomycin resistance between Enterococcus faecium strains.
Hanrahan J J Hoyen C C Rice L B LB
Antimicrobial agents and chemotherapy 20000501 5
In several clonally unrelated VanB-type vancomycin-resistant Enterococcus faecium strains, we demonstrated a common physical relationship between pbp5 and Tn5382 as well as common mutations within pbp5. The majority of these strains transferred vancomycin and ampicillin resistance to E. faecium in vitro, suggesting the dissemination of similar transferable pbp5-vanB-containing mobile elements throughout the United States. ...[more]
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