Ontology highlight
ABSTRACT:
SUBMITTER: Bi S
PROVIDER: S-EPMC8987372 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Bi Shengyu S Jia Fenglin F Lv Chang C He Qiang Q Xu Xinyu X Xue Zhixiao Z Su Siying S
Frontiers in cardiovascular medicine 20220324
Pulsed field ablation (PFA) is a novel method of pulmonary venous isolation in atrial fibrillation ablation and is featured by tissue-selective ablation. Isolation is achieved via the application of high-voltage microsecond pulses that create irreversible perforations in cell membranes (i.e., electroporation). We proposed a new biphasic asymmetric pulse mode and verified the lesion persistence and safety of this mode for pulmonary vein ostia ablation in preclinical studies. We found that biphasi ...[more]