Ontology highlight
ABSTRACT:
SUBMITTER: Montasser ME
PROVIDER: S-EPMC8989972 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Montasser May E ME Aslibekyan Stella S Srinivasasainagendra Vinodh V Tiwari Hemant K HK Patki Amit A Bagheri Minoo M Kind Tobias T Barupal Dinesh Kumar DK Fan Sili S Perry James J Ryan Kathleen A KA Shuldiner Alan R AR Arnett Donna K DK Beitelshees Amber L AL Irvin Marguerite Ryan MR O'Connell Jeffrey R JR
Communications biology 20220407 1
Identifying the genetic determinants of inter-individual variation in lipid species (lipidome) may provide deeper understanding and additional insight into the mechanistic effect of complex lipidomic pathways in CVD risk and progression beyond simple traditional lipids. Previous studies have been largely population based and thus only powered to discover associations with common genetic variants. Founder populations represent a powerful resource to accelerate discovery of previously unknown biol ...[more]