Dataset Information

Partial COVID-19 vaccination associated with reduction in postoperative mortality and SARS-CoV-2 infection.

ABSTRACT:

Background

There are currently no data to guide decisions about delaying surgery to achieve full vaccination.

Methods

We analyzed data from patients undergoing surgery at any of the 1,283 VA medical facilities nationwide and compared postoperative complication rates by vaccination status.

Results

Of 87,073 surgical patients, 20% were fully vaccinated, 15% partially vaccinated, and 65% unvaccinated. Mortality was reduced in full vaccination vs. unvaccinated (Incidence Rate Ratio 0.77, 95% CI [0.62, 0.94]) and partially vaccinated vs. unvaccinated (0.75 [0.60, 0.94]). Postoperative COVID-19 infection was reduced in fully (0.18 [0.12, 0.26]) and partially vaccinated patients (0.34 [0.24, 0.48]). Fully vaccinated compared to partially vaccinated patients, had similar postoperative mortality (1.02, [0.78, 1.33]), but had decreased COVID-19 infection (0.53 [0.32, 0.87]), pneumonia (0.75 [0.62, 0.93]), and pulmonary failure (0.79 [0.68, 0.93]).

Conclusions

Full and partial vaccination reduces postoperative complications indicating the importance of any degree of vaccination prior to surgery.

SUBMITTER: Prasad NK

PROVIDER: S-EPMC8993410 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature

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Publications

Partial COVID-19 vaccination associated with reduction in postoperative mortality and SARS-CoV-2 infection.

Prasad Nikhil K NK Englum Brian R BR Mayorga-Carlin Minerva M Turner Douglas J DJ Sahoo Shalini S Sorkin John D JD Lal Brajesh K BK

American journal of surgery 20220408 4

<h4>Background</h4>There are currently no data to guide decisions about delaying surgery to achieve full vaccination.<h4>Methods</h4>We analyzed data from patients undergoing surgery at any of the 1,283 VA medical facilities nationwide and compared postoperative complication rates by vaccination status.<h4>Results</h4>Of 87,073 surgical patients, 20% were fully vaccinated, 15% partially vaccinated, and 65% unvaccinated. Mortality was reduced in full vaccination vs. unvaccinated (Incidence Rate R ...[more]

PMID: 35465949

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Dataset Information

Partial COVID-19 vaccination associated with reduction in postoperative mortality and SARS-CoV-2 infection.

Background

Methods

Results

Conclusions

Publications

Partial COVID-19 vaccination associated with reduction in postoperative mortality and SARS-CoV-2 infection.

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