Ontology highlight
ABSTRACT:
SUBMITTER: Motyan JA
PROVIDER: S-EPMC8998604 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
Mótyán János András JA Mahdi Mohamed M Hoffka Gyula G Tőzsér József J
International journal of molecular sciences 20220323 7
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome 2 (SARS-CoV-2), has been one of the most devastating pandemics of recent times. The lack of potent novel antivirals had led to global health crises; however, emergence and approval of potent inhibitors of the viral main protease (Mpro), such as Pfizer's newly approved nirmatrelvir, offers hope not only in the therapeutic front but also in the context of prophylaxis against the infection. By their nature, RNA vir ...[more]