Ontology highlight
ABSTRACT:
SUBMITTER: Furusawa H
PROVIDER: S-EPMC9013199 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Furusawa Haruhiko H Peljto Anna L AL Walts Avram D AD Cardwell Jonathan J Molyneaux Philip L PL Lee Joyce S JS Fernández Pérez Evans R ER Wolters Paul J PJ Yang Ivana V IV Schwartz David A DA
Thorax 20220107 5
A subset of patients with hypersensitivity pneumonitis (HP) develop lung fibrosis that is clinically similar to idiopathic pulmonary fibrosis (IPF). To address the aetiological determinants of fibrotic HP, we investigated whether the common IPF genetic risk variants were also relevant in study subjects with fibrotic HP. Our findings indicate that common genetic variants in <i>TERC</i>, <i>DSP</i>, <i>MUC5B</i> and <i>IVD</i> were significantly associated with fibrotic HP. These findings provide ...[more]