The FAR protein family of parasitic nematodes.
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ABSTRACT:
SUBMITTER: Parks SC
PROVIDER: S-EPMC9022830 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Publications
The FAR protein family of parasitic nematodes.
Parks Sophia C SC Nguyen Susan S Boulanger Martin J MJ Dillman Adler R AR
PLoS pathogens 20220421 4
Fatty acid-and retinol-binding proteins (FARs) belong to a unique family of excreted/secreted proteins (ESPs) found exclusively in nematodes. Much of our understanding of these proteins, however, is limited to their in vitro binding characteristics toward various fatty acids and retinol and has provided little insight into their in vivo functions or mechanisms. Recent research, however, has shown that FARs elicit an immunomodulatory role in plant and animal model systems, likely by sequestering ...[more]
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