Ontology highlight
ABSTRACT:
SUBMITTER: Thierauf JC
PROVIDER: S-EPMC9026998 | biostudies-literature | 2022 Apr
REPOSITORIES: biostudies-literature
Thierauf Julia C JC Farahani Alex A AA Indave B Iciar BI Bard Adam Z AZ White Valerie A VA Smith Cameron R CR Marble Hetal H Hyrcza Martin D MD Chan John K C JKC Bishop Justin J Shi Qiuying Q Ely Kim K Agaimy Abbas A Martinez-Lage Maria M Nose Vania V Rivera Miguel M Nardi Valentina V Dias-Santagata Dora D Garg Salil S Sadow Peter P Le Long P LP Faquin William W Ritterhouse Lauren L LL Cree Ian A IA Iafrate A John AJ Lennerz Jochen K JK
International journal of molecular sciences 20220413 8
Mucoepidermoid carcinoma (MEC) is often seen in salivary glands and can harbor MAML2 translocations (MAML2+). The translocation status has diagnostic utility as an objective confirmation of the MEC diagnosis, for example, when distinction from the more aggressive adenosquamous carcinoma (ASC) is not straightforward. To assess the diagnostic relevance of MAML2, we examined our 5-year experience in prospective testing of 8106 solid tumors using RNA-seq panel testing in combinations with a two-roun ...[more]